After restraint stress, mice with high and low immobility time have a different neurochemical and behavioral profile

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Thiago Reis-Silva
Ana Paula Lima
Natalia Moreira
Atilio Calefi
Thaísa Meira Sandini
Jorge Camilo Florio
Maria Martha Bernardi

Abstract

High and low immobility on the tail suspension test is a common tool for assessing antidepressant drug effects. However, those parameters might be a natural phenotype present in the mice population and could be selected through behavior evaluation without an induced-drug behavior need. High immobility has been also related to depressed-like behavior, that in humans are characterized by wide range of symptoms, such as anhedonia, anxiety and tiredness. 

Article Details

Section

SEMANA CIENTÍFICA PROF. DR. BENJAMIN EURICO MALUCELLI

How to Cite

After restraint stress, mice with high and low immobility time have a different neurochemical and behavioral profile. Revista de Educação Continuada em Medicina Veterinária e Zootecnia, [S. l.], v. 14, n. 1, p. 57–57, 2016. Disponível em: https://www.revistamvez-crmvsp.com.br/index.php/recmvz/article/view/31107. Acesso em: 6 dec. 2025.