After restraint stress, mice with high and low immobility time have a different neurochemical and behavioral profile

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Thiago Reis-Silva
Ana Paula Lima
Natalia Moreira
Atilio Calefi
Thaísa Meira Sandini
Jorge Camilo Florio
Maria Martha Bernardi

Resumo

High and low immobility on the tail suspension test is a common tool for assessing antidepressant drug effects. However, those parameters might be a natural phenotype present in the mice population and could be selected through behavior evaluation without an induced-drug behavior need. High immobility has been also related to depressed-like behavior, that in humans are characterized by wide range of symptoms, such as anhedonia, anxiety and tiredness. 

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Como Citar
REIS-SILVA, T.; LIMA, A. P.; MOREIRA, N.; CALEFI, A.; SANDINI, T. M.; FLORIO, J. C.; BERNARDI, M. M. After restraint stress, mice with high and low immobility time have a different neurochemical and behavioral profile. Revista de Educação Continuada em Medicina Veterinária e Zootecnia do CRMV-SP, v. 14, n. 1, p. 57-57, 3 jun. 2016.
Palavras-chave
stress; mice; behavior; animal
Seção
SEMANA CIENTÍFICA PROF. DR. BENJAMIN EURICO MALUCELLI